Proton Radiotherapy Offers Immune-Sparing Benefits in Glioblastoma Treatment

20261 citationsJournal Articlehybrid Open Access

Authors

J. Coupey · Centre National de la Recherche Scientifique

T.N. Pham · Centre National de la Recherche Scientifique

J. Toutain · Centre National de la Recherche Scientifique

V. Ivanova · Centre National de la Recherche Scientifique

E.S. Hue · Normandie Université

C. Helaine · Centre National de la Recherche Scientifique

A. Ismail

Abstract

Understanding how brain irradiation affects circulating immunity can inform strategies to improve brain tumor treatment. This involves combining irradiation with immunotherapy and adjusting clinical protocols to restore lymphocytes/boost antitumor T cells.

Topics & Keywords

Glioma Diagnosis and Treatment Cancer Immunotherapy and Biomarkers Immunotherapy and Immune Responses

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Radiation Oncology*Biology*Physics

DOI: 10.1016/j.ijrobp.2025.12.051

Field-Weighted Citation Impact: 38.95