The Influence of Left Ventricular Ejection Fraction on Long-Term Survival of Patients after Transcatheter Edge-to-Edge Mitral Valve Repair

LVEF demonstrated limited prognostic value for long-term outcomes following M-TEER, challenging its role as a standalone marker in this population. Procedural safety and efficacy were consistent across subgroups, underscoring the viability of M-TEER in surgically inoperable patients. Given the significant higher in-hospital mortality rate due to non-cardiac causes in the HFrEF subgroup, tailored therapeutic strategies addressing the underlying diseases should be pursued to optimize outcomes. Future studies should explore possible improvements in risk assessment and patient selection, for example, by integrating emerging imaging modalities and accounting for comorbidities, to improve treatment outcomes.