Cancer Risk and Mortality Following Kaposi Sarcoma Among People with HIV in the United States, 2000 to 2019

People with HIV (PWH) have increased Kaposi sarcoma (KS) risk. Among 2,645 PWH with KS in the United States HIV/AIDS Cancer Match Study, subsequent cancer risk was elevated 2.8-fold (95% confidence interval [CI]: 2.4-3.3) compared to PWH without KS. Mortality after KS declined 2000-2002 and 2012-2015 (hazard ratio = 0.64; 95%CI: 0.55-0.74).