Beyond the surface: soluble SIGLEC-1 as a clinically applicable type I IFN biomarker

20261 citationsJournal Article

Authors

Jakob Severin Cepus · Humboldt-Universität zu Berlin

Julia Maria Klemens · Euroimmun Medizinische Labordiagnostika (Germany)

Matthias Block · Euroimmun Medizinische Labordiagnostika (Germany)

Philipp Enghard · Leibniz Association

Tobias Alexander · Leibniz Association

Andreas Grützkau · Leibniz Association

G. Krönke

Abstract

Our study supports sSIGLEC-1 as a reliable and scalable biomarker of IFN-I activity in SLE. Its performance and compatibility with routine assays make it a strong candidate for clinical translation and broader application in IFN-I-driven diseases.

Topics & Keywords

Systemic Lupus Erythematosus Research interferon and immune responses Rheumatoid Arthritis Research and Therapies

Publication Details

Published in: Lara D. Veeken

Volume 65, Issue 2

DOI: 10.1093/rheumatology/keag027

Field-Weighted Citation Impact: 50.13

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Beyond the surface: soluble SIGLEC-1 as a clinically applicable type I IFN biomarker

Authors

Abstract

Topics & Keywords

Publication Details