Etiology of Severe Microcephaly in Infants: A Multinational Surveillance Study

20260 citationsJournal Article

Authors

Daniel Farrar · Hospital for Sick Children

Rachel L Knowles · Great Ormond Street Hospital

Carlos Víquez · The University of Sydney

Gareth Baynam · The Kids Research Institute Australia

Ari Bitnun · University of Toronto

Mavis Duncanson · Dunedin Public Hospital

Richard M. Lynn

Abstract

At least one-half of severe microcephaly cases are attributable to genetic causes. One-third had unknown etiology, highlighting a need for a systematic approach to diagnostic investigation, including genomic sequencing and brain imaging for all children with severe microcephaly.

Topics & Keywords

Infectious Encephalopathies and Encephalitis Epilepsy research and treatment Mosquito-borne diseases and control

Publication Details

Published in: PEDIATRICS

Volume 157, Issue 2

DOI: 10.1542/peds.2025-072700

Field-Weighted Citation Impact: 0.00

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Etiology of Severe Microcephaly in Infants: A Multinational Surveillance Study

Authors

Abstract

Topics & Keywords

Publication Details