Effect of Preoperative Steroid Injection on Wound Drainage after Modified Radical Mastectomy

Objective: The aim of this study was to determine the Effect of Preoperative Steroid Injection on Wound Drainage after Modified Radical Study Design and Setting: The current Quasi-experimental study was carried out at the department of surgery Ibn e siena hospital and research institute Multan and Bakhtawar Ameen Medical and Dental College Multan for a period of six months from January, 2023 -June, 2024 after taking permission from the ethical board of the hospital. Methodology: A total of 62 females with breast cancer, planned for modified radical mastectomy were included. The patients were assigned computer-generated numbers to form two equal groups, A and B. An hour before to surgery, group A received a 120 mg a day (3 ml) injection of depomedrol, while group B received 3 ml of regular saline. The same consultant surgeon conducted MRM on both groups using the same dissection technique, which is steel scalpel dissection. Two suction drains, one at the breast site and one at the axillary area, were positioned at the end of the treatment. Data was analyzed through SPSS 25. Results: In our study, 48.3% females were diagnosed with stage II, and 51.7% had stage I breast cancer. In a modified radical mastectomy, a single preoperative steroid dose reduced mean drainage volume more than control. (P=0.048). Conclusion: Our findings showed that that the preventive steroid injections prescription in women following modified radical mastectomy were more effective in lowering mean drainage volume for female participants with stage I and II breast cancer when compared to normal saline