Immunophenotyping TCF1-expressing TILs: spatial profiling and prognostic value in operable non-small cell lung cancer

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Authors

Konstantinos Ntostoglou · Hellenic Oncology Research Group

Georgios Christodoulopoulos · University Hospital of Larissa

Katie Stoker · Department of Physics, Mathematics and Informatics

Jean Descarpentrie · Umeå University

Anastasia Xagara · University Hospital of Larissa

Dora Chatzidaki · Hellenic Oncology Research Group

Vasiliki Anastasopoulou

Abstract

Our findings support a more refined framework for TCF1<sup>+</sup> TIL assessment and TCF1 expression across cellular populations in the tumor microenvironment, with implications for prognostication in operable NSCLC.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Single-cell and spatial transcriptomics Immunotherapy and Immune Responses

Publication Details

Published in: Frontiers in Immunology

Volume 17, pp. 1731337-1731337

DOI: 10.3389/fimmu.2026.1731337

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Immunophenotyping TCF1-expressing TILs: spatial profiling and prognostic value in operable non-small cell lung cancer

Authors

Abstract

Topics & Keywords

Publication Details