Methylglyoxal‐derived hydroimidazolone ( <scp>MG</scp> ‐ <scp>H1</scp> ) is a novel marker of insulin resistance in Japanese individuals, disturbing insulin signalling via <scp>mTORC2</scp> in cultured myocytes

In clinical study findings revealed that postprandial MG-H1 was a novel marker of insulin resistance in Japanese individuals, and in vitro findings using cultured C2C12 skeletal myocytes suggested that MG-H1 disturbs insulin signalling via the mechanisms of mTORC2 activation.