Combining OCT and OCT angiography improves differentiation of mild cognitive impairment and Alzheimer’s disease

20260 citationsJournal Articlegold Open Access

Authors

Jacqueline Chua · National University of Singapore

Suman Singh · Singapore Eye Research Institute

Shiyuan Gong · Tsinghua University

Damon Wong · National University of Singapore

Bingyao Tan · National University of Singapore

An Qi Toh · National University of Singapore

Narayanaswamy Venketasubramanian

Abstract

Integrating OCT- and OCTA-derived metrics significantly improved discriminative performance compared with either modality alone, underscoring their complementary value in capturing distinct structural and vascular alterations associated with cognitive impairment.

Topics & Keywords

Optical Coherence Tomography Applications Retinal Imaging and Analysis Retinal Diseases and Treatments

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Alzheimer s Research & Therapy

Volume 18, Issue 1, pp. 39-39

DOI: 10.1186/s13195-026-01955-3

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