Corneal Stromal Thinning and Posterior Irregularity After DMEK: Clinical Observations and Biophysical Hypotheses

20260 citationsJournal Articlehybrid Open Access

Authors

Alfredo Borgia · University of Liverpool

Matteo Airaldi · University of Liverpool

Sabrina Vaccaro · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

David Lockington · Gartnavel General Hospital

Filippo Lozza · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

Francesco Semeraro · Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia

Abstract

Greater reductions in corneal thickness are associated with postoperative stromal thinning and hyperopic shift after DMEK. Preoperative stromal ripples are associated with greater reductions in corneal thickness after DMEK. Stromal remodeling appears influenced by endothelial recovery and preoperative biomechanical status, supporting emerging hypotheses on keratocyte loss and osmotic imbalance.

Topics & Keywords

Corneal surgery and disorders Corneal Surgery and Treatments Glaucoma and retinal disorders

Publication Details

Published in: Cornea

DOI: 10.1097/ico.0000000000004084

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Corneal Stromal Thinning and Posterior Irregularity After DMEK: Clinical Observations and Biophysical Hypotheses

Authors

Abstract

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Publication Details