First characterization of insertions in the HIV-1 integrase-coding region from people with HIV

20250 citationsJournal Article

Authors

Nhat Quang Tu · Centre National de la Recherche Scientifique

Thomas Montrouge · Délégation Paris 5

Gladys Mbemba · Centre National de la Recherche Scientifique

Melissa Stampetta · Centre National de la Recherche Scientifique

Magali Bouvier‐Alias · Centre Hospitalier Universitaire Henri-Mondor

Véronique Avettand-Fenoël · Centre National de la Recherche Scientifique

Audrey Mirand

Abstract

Our study has revealed that the mutations observed in people living with HIV-1 do not confer resistance to anti-integrase compounds but are detrimental to viral replication.

Topics & Keywords

HIV/AIDS drug development and treatment Biochemical and Molecular Research Calcium signaling and nucleotide metabolism

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Antimicrobial Chemotherapy

Volume 81, Issue 2

DOI: 10.1093/jac/dkaf491

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