Modern Clinical Guidelines for the Management of Patients with Gastroesophageal Reflux Disease

Gastroesophageal reflux disease (GERD) is a chronic condition with recurrent retrograde flow of gastric contents to esophagus due to impaired lower esophageal sphincter function. It leads to typical symptoms such as heartburn, regurgitation, and dysphagia, as well as non-specific manifestations such as cough, sore throat, retrosternal pain. Implementation of modern diagnostic methods and personalized therapeutic strategies can significantly reduce symptoms, prevent complications, and improve quality of life of patients with GERD. The presented clinical guidelines describe integrated approach to diagnosis including history taking, physical examination, and imaging studies. Differential diagnosis with other diseases with similar symptoms is crucial as well. GERD management should be systemic and include non-pharmacological measures: lifestyle correction and drug therapy (antacids, proton pump inhibitors, and prokinetics). Particular attention is paid to complications prevention. These guidelines are the basis for timely and comprehensive management for GERD patients.