Quantitative Comparison of Multi‐Echo Spin Echo and Multi‐Echo Gradient Echo Myelin Water Imaging in a Panel of <scp> <i>Mbp</i> </scp> Enhancer‐Edited Mouse Lines

Both MESE and MGRE sequences provide biologically meaningful estimates of myelin content in fixed tissue but exhibit contrast-specific sensitivities and biases. MGRE combined with rPCA offers time efficient imaging and robustness in fine white matter structures, supporting its utility for high-resolution preclinical myelin mapping.