Molecular characteristics and Helicobacter pylori infection rates in patients with gastric cancer in Western Poland: a comparative analysis of gastrectomy specimens across two decades

Despite advancements in H. pylori research and technology over 20 years, no improvement was observed in H. pylori-positive tumor rates or early gastric cancer detection in Western Poland. Although molecular characteristics remained largely unchanged, the increased proliferation index in recently diagnosed cancers merits further study.