Clinical Signs Associated With Mortality and Sepsis in Young Infants

20260 citationsJournal Article

Authors

Sophie Driker · Brigham and Women's Hospital

Sitarah Mathias · Boston Children's Hospital

Alastair Fung · Hospital for Sick Children

Suci Ardini Widyaningsih · Brigham and Women's Hospital

Naomi Schmeck · Brigham and Women's Hospital

Jana Adnan · Massachusetts General Hospital

Yumin Kim

Abstract

All current WHO IMCI clinical signs were significantly associated with mortality or culture-confirmed sepsis. Several signs not in IMCI were identified that may improve identification of life-threatening illness in young infants in resource-limited settings where clinical sign algorithms are the primary diagnostic tool.

Topics & Keywords

Neonatal and Maternal Infections Sepsis Diagnosis and Treatment Neonatal Respiratory Health Research

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: JAMA Pediatrics

DOI: 10.1001/jamapediatrics.2025.5967

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