Association between atherosclerosis and atrial fibrillation progression in patients with paroxysmal atrial fibrillation: Data from the RACE V study

In patients with paroxysmal AF, 65% of patients had atherosclerosis. Atherosclerosis was a determinant of AF progression after adjustment for established risk factors and comorbidities, suggesting that vascular disease may contribute directly to atrial remodelling and arrhythmia persistence.