Verschiedene immunologische Typen der CRSwNP im Kontext der neuen Europäischen EAACI-Nomenklatur

Expansion of the immunological classification to include type VI hypersensitivity reactions represents an important step toward a better understanding of the pathophysiology of CRSwNP. Identifying these specific reaction patterns-particularly those triggered by chemical substances-highlights the complexity of the underlying immune mechanisms and emphasizes the need for endotype-based diagnostics. Incorporating these insights into clinical practice allows for more targeted individualized therapies and marks another step toward personalized medicine in CRS.