Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models

20260 citationsJournal Articlegold Open Access

Authors

Yoshiaki Tanji · Jikei University School of Medicine

Shu Shimada · Institute of Medicinal Molecular Design

Megumi Kato · Tokyo Institute of Psychiatry

Yoshimitsu Akiyama · Tokyo Institute of Psychiatry

Megumi Hatano · Tokyo Institute of Psychiatry

Shu Tsukihara · Jikei University School of Medicine

Yosuke Igarashi

Abstract

This work was supported by Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT), Japan Agency for Medical Research and Development (AMED), and the Princess Takamatsu Cancer Research Fund.

Topics & Keywords

Immunotherapy and Immune Responses CAR-T cell therapy research Cancer Immunotherapy and Biomarkers

Publication Details

Published in: EBioMedicine

Volume 125, pp. 106137-106137

DOI: 10.1016/j.ebiom.2026.106137

Field-Weighted Citation Impact: 0.00

Command Palette

Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models

Authors

Abstract

Topics & Keywords

Publication Details