Dysregulated miRNAs and downstream gene expression associated with poor treatment response in first-episode psychosis

20260 citationsJournal Articlegold Open Access

Authors

Shun-Chun Yu · National Health Research Institutes

Yun-Chu Wang · National Health Research Institutes

Hsiu-Ping Lin · National Health Research Institutes

Ya-Wen Jen · National Taiwan University

Tzung-Jeng Hwang · National Taiwan University

Chih-Min Liu · National Taiwan University Hospital

Hung-Yu Chan ·

Abstract

Our multi-omics approach helps identify miRNAs and their downstream target genes associated with FEP patients' poor responses to antipsychotics, highlighting potential biomarkers for personalized therapy.

Topics & Keywords

MicroRNA in disease regulation Phosphodiesterase function and regulation Tryptophan and brain disorders

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Brain Behavior & Immunity - Health

Volume 52, pp. 101190-101190

DOI: 10.1016/j.bbih.2026.101190

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