Perspectives of HIV Prevention Policymakers, Health Care Workers and Community Workers Concerning PrEP Implementation in Cambodia: The ANRS Quali-PrEP Study

This study aimed to explore the perspectives of actors in human immunodeficiency virus (HIV) prevention concerning pre-exposure prophylaxis (PrEP) in Cambodia. Interviews with national-level policymakers and focus groups with service providers (health care workers and community-based organization [CBO] workers) providing care to key populations (KPs) were conducted in 2022. Actors viewed pre-exposure prophylaxis as an effective tool for reducing HIV transmission among KPs and were committed to its implementation. However, they were concerned about KPs' lack of protection against sexually transmitted infections other than HIV and about unintended pregnancies, as well as potential challenges to PrEP adherence and associated side effects. Key barriers to implementation included funding shortages, difficulties in reaching mobile KPs, and the need for further training for service providers. This study revealed the strong commitment to PrEP of actors in HIV prevention in Cambodia, and the need for community-centered approaches to ensure that sexual and reproductive health services best meet KPs' needs.