Temporal trends and regional variations in hepatocellular carcinoma etiology: a multinational study across Asia

20260 citationsJournal Articlehybrid Open Access

Authors

Yasuto Takeuchi · Okayama University

Ryosuke Tateishi · University of Tokyo Hospital

Shuntaro Obi · Teikyo University Chiba Medical Center

M. Otsuka · Okayama University

Hitoshi Mochizuki · Yamanashi Prefectural Central Hospital

Amarsanaa Jazag · Mongolian National University of Medical Sciences

Osamu Yokosuka

Abstract

Distinct regional patterns and temporal changes in HCC etiology across Asia highlight the need for tailored prevention and surveillance measures. The growing burden of MAFLD-related HCC emphasizes its emerging role in liver cancer development, particularly in regions with declining viral hepatitis.

Topics & Keywords

Hepatocellular Carcinoma Treatment and Prognosis Hepatitis C virus research Liver Disease Diagnosis and Treatment

UN Sustainable Development Goals

Partnerships for the goals

Publication Details

Published in: Hepatology International

DOI: 10.1007/s12072-026-11037-z

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