Combined azelastine fluticasone nasal spray versus fluticasone propionate nasal spray in postoperative management of central compartment atopic disease (CCAD)

The present research shows that nasal sprays may effectively reach the target areas in the central compartment after surgery, potentially benefiting from the widened post-surgical nasal corridor. Combined steroid/H1 blocker sprays provided better postoperative control of CCAD than steroid sprays. The synergistic action of H1 blockers in the combined sprays confirms the association between CCAD and nasal allergy and encourages us to consider it as a first line treatment for the disease.