Intrinsic Gravitation as a Physical Layer of Genetic Expression Mass, Torque, and Repeatability from RNA Dynamics to Development

Classical genetics interprets DNA and RNA primarily as informational polymers whose biological effects arise from nucleotide sequence and biochemical interactions. However, nucleic acids are also physical entities possessing mass, density, spatial extent, and rotational degrees of freedom, operating within environments governed by universal physical laws. This article proposes that intrinsic gravitation and mass-dependent mechanics constitute a complementary physical layer of genetic expression, acting alongside electrochemical interactions rather than replacing them. Drawing on conservation of angular momentum as a unifying principle, a cross-scale framework is developed linking nucleotide mass asymmetry, RNA rotational dynamics, chromatin compaction, developmental robustness, and threshold phenomena in embryogenesis. Sex differentiation and trisomy 21 (Down syndrome) are discussed as illustrative developmental cases of localized genomic mass asymmetry, without challenging established genetic causation.