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Structural basis for pan-coronavirus inhibition of 3CL protease

20260 citationsJournal Article

Authors

Eswar R. Reddem · Columbia University

F. Forouhar · Columbia University Irving Medical Center

Cheng Liu · Rapt Therapeutics (United States)

Sarah K. Stevens · Rapt Therapeutics (United States)

Andreas Jekle · Rapt Therapeutics (United States)

Ching-Wen Chang · Hackensack Meridian Health

Topics & Keywords

SARS-CoV-2 and COVID-19 Research Computational Drug Discovery Methods Diverse Scientific Research Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Structure

DOI: 10.1016/j.str.2026.01.003

Field-Weighted Citation Impact: 0.00

Structural basis for pan-coronavirus inhibition of 3CL protease | Researchclopedia

· Hackensack Meridian Health

David C. McGowan

David C. Smith · Rapt Therapeutics (United States)

Pierre Raboisson

Leonid Beigelman · Rapt Therapeutics (United States)

Phinikoula S. Katsamba · Columbia University

Fabiana Bahna · Columbia University

Seetha Mannepalli · Columbia University

Lawrence M. Blatt · Rapt Therapeutics (United States)

David Perlin · Center for Discovery

Julian Symons · Rapt Therapeutics (United States)

Lawrence Shapiro · Columbia University

Antitsa Stoycheva · Align Technology (United States)