The expression pattern and prognostic relevance of p120-catenin, COL4A2 and SOX10 in glioma

20260 citationsJournal Articlegold Open Access

Authors

Claudia A. Dumitru · Otto-von-Guericke University Magdeburg

David Markus Andreas Schmidt · Otto-von-Guericke University Magdeburg

Belal Neyazi · Otto-von-Guericke University Magdeburg

Klaus-Peter Stein · Otto-von-Guericke University Magdeburg

A.M. Rashidi · Otto-von-Guericke University Magdeburg

Ulf D. Kahlert · Otto-von-Guericke University Magdeburg

C. Mawrin

Abstract

p120-catenin is a potential tumor-promoting factor in glioma, and a prognostic marker in GBM. In contrast, COL4A2 and SOX10 appear to act as tumor suppressors in glioma pathophysiology. SOX10 may additionally be a valuable prognostic marker in female GBM patients.

Topics & Keywords

Glioma Diagnosis and Treatment Cell Adhesion Molecules Research Wnt/β-catenin signaling in development and cancer

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Frontiers in Oncology

Volume 16, pp. 1769786-1769786

DOI: 10.3389/fonc.2026.1769786

Field-Weighted Citation Impact: 0.00