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DesCartes Builder is a tool to create digital twin (DT) pipelines using the Function+Data Flow (FDF) domain-specific language for machine-learning-based DT modeling. It provides three high-level features: visual specification of the DT pipeline with implicit typing to detect common errors, automatic generation of executable models from the FDF specification, validation of design goals and ML models. Installers for Windows/macOS/Linux are available alongside documentation (`BUILDER_DOC.pdf`). The sources are available at: Front-end: https://github.com/CPS-research-group/descartes-builder Back-end: https://github.com/CPS-research-group/kedro-umbrella The tool is described in details at E. de Conto, B. Genest, A. Easwaran, N. Ng and S. Menon, "DesCartes Builder: A Tool to Develop Machine-Learning Based Digital Twins," 2025 ACM/IEEE 28th International Conference on Model Driven Engineering Languages and Systems Companion (MODELS-C), Grand Rapids, MI, USA, 2025, pp. 129-133, doi: 10.1109/MODELS-C68889.2025.00028. AcknowledgmentsThis research is part of the program DesCartes and is supported by the National Research Foundation, Prime Minister’s Office, Singapore, under its Campus for Research Excellence and Technological Enterprise (CREATE) program.