TCRcloud: a global visualization tool for T-cell and B-cell receptor transcripts

TCRcloud enables to i) intuitively visualize molecular TCR compositions, ii) combine different TCR repertoire measurements within a single radar plot to capture biologically relevant TCR indices in a single image iii) visualize the usage of the V-genes and iv) visualize the frequency of amino acids in the CDR3. This easy to use tool enables to intuitively visualize changes in bulk TCR and BCR compositions in association with immunotherapies in a spatio-temporal fashion.