Spatial transcriptomics identifies IL-32 as a lipid droplet-associated cytokine linked to tubular injury in human diabetic kidney disease

20260 citationsJournal Articlehybrid Open Access

Authors

Kieran Meadows · University of Calgary

Hyunjae Chung · University of Calgary

Sa Vo · Human BioMolecular Research Institute

Aysa Imanzadeh · University of Calgary

Heewon Seo · University of Calgary

Sisay Getie Belay · University of Calgary

Asha Swamy ·

Abstract

IL-32 is a LD-associated cytokine upregulated during tubular injury that represents a potential link between lipid dysregulation, inflammation and progression in human DKD.

Topics & Keywords

IL-33, ST2, and ILC Pathways Cytokine Signaling Pathways and Interactions Psoriasis: Treatment and Pathogenesis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Inflammation Research

Volume 75, Issue 1, pp. 33-33

DOI: 10.1007/s00011-026-02192-y

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