Is nitazene-related mortality underestimated? Findings from an <i>in vivo</i> and <i>ex vivo</i> rat study and pharmacoepidemiological analysis of coroner-reported deaths

Nitazene-related deaths have increased in England, Wales, and Northern Ireland, and may have been underestimated due to post-mortem instability. Urgent public health action is required to reduce nitazene-related harms.