Genomic analysis of coexisting β-lactamase plasmids in Klebsiella pneumoniae from an immunocompromised patient

20260 citationsJournal Articlegold Open Access

Authors

Thamer M Brek · Jazan University

Hanan A. Alshafie · Prince Mohammed bin Abdulaziz Hospital

Musa A Ayashi · Prince Mohammed bin Abdulaziz Hospital

Othman I. Aljurayyad · Ministry of Environment and Climate Change

Hatim Almutairi · Ministry of Environment and Climate Change

Elaf M Alattas · King Fahad Central Hospital

Ibrahim A. Al-Zaharani

Abstract

Genomic profiling of KP-JZ177 reveals high-risk K. pneumoniae clone carrying extensive resistance and virulence determinants on multiple plasmids, including bla<sub>OXA-48</sub> and bla<sub>NDM-1</sub>. Its plasmids similarity to geographically distant strains underscore global AMR circulation, emphasizing the need for enhanced surveillance of ST147 CRKP isolates in high-risk populations.

Topics & Keywords

Antibiotic Resistance in Bacteria Pneumonia and Respiratory Infections Nosocomial Infections in ICU

Publication Details

Published in: Journal of Global Antimicrobial Resistance

Volume 47, pp. 73-78

DOI: 10.1016/j.jgar.2026.02.002

Field-Weighted Citation Impact: 0.00

Command Palette

Genomic analysis of coexisting β-lactamase plasmids in Klebsiella pneumoniae from an immunocompromised patient

Authors

Abstract

Topics & Keywords

Publication Details