A novel internal reference microorganism-based method reveals wild-enriched Penicillium for enhancing growth and disease resistance in Fritillaria thunbergii

This study established the IRM-RADMA method and identified key <i>Penicillium</i> strains from the wild <i>Fritillaria thunbergii</i> rhizosphere. Their confirmed dual functions in growth promotion and disease suppression validate the 'plant microbiome rewilding' strategy, offering a new paradigm for the biological control of <i>F. thunbergii</i> diseases.