From bioinformatic identification to functional validation: MMP25 as a pro-inflammatory mediator in osteoarthritis

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Authors

Ting Wu · Integrated Chinese Medicine (China)

Shenyi Lu · Affiliated Hospital of Youjiang Medical University for Nationalities

Abstract

MMP25 may serve as a potential biomarker for evaluating knee osteoarthritis and it appears to mediate IL-1β-induced chondrocyte injury and extracellular matrix degradation.

Topics & Keywords

Osteoarthritis Treatment and Mechanisms Connective Tissue Growth Factor Research Rheumatoid Arthritis Research and Therapies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Orthopaedic Surgery and Research

Volume 21, Issue 1

DOI: 10.1186/s13018-026-06732-4

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