Development and Validation of a Computational Histology Artificial Intelligence–Powered Predictive Biomarker for Selection of Chemotherapy in Advanced Pancreatic Cancer

20260 citationsJournal Article

Authors

Andrew E. Hendifar · Cedars-Sinai Medical Center

Viswesh Krishna

Vrishab Krishna

Haochen Zhang

Asit Tarsode

Vivek Nimgaonkar · Johns Hopkins University

Katelyn Smith · University of Pittsburgh Medical Center

Kawther Abdilleh · Pancreatic Cancer Action Network

Snehal Sonawane

Abstract

The histomorphology-based GvF biomarker predicted differential treatment benefit of first-line GvF. This biomarker can guide optimal treatment selection for first-line therapy in advanced PDAC.

Topics & Keywords

Pancreatic and Hepatic Oncology Research AI in cancer detection Mathematical Biology Tumor Growth

Publication Details

Published in: Journal of Clinical Oncology

DOI: 10.1200/jco-25-02199

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Development and Validation of a Computational Histology Artificial Intelligence–Powered Predictive Biomarker for Selection of Chemotherapy in Advanced Pancreatic Cancer

Authors

Abstract

Topics & Keywords

Publication Details