Antibiotic Use Linked to Worse Outcomes in Patients With Gastrointestinal and Liver Cancer on Immune Checkpoint Inhibitors: A Meta-Analysis

20260 citationsJournal Article

Authors

Mohammad Saeid Rezaee-Zavareh · Middle East Liver Disease Center

Hamidreza Karimi-Sari · Johns Hopkins University

Peyvand Parhizkar Roudsari · Tehran University of Medical Sciences

Osama Khattab · Cedars-Sinai Medical Center

Abdelrahman M. Attia · Cedars-Sinai Medical Center

Pojsakorn Danpanichkul · Texas Tech University

Soo Young Hwang

Abstract

Antibiotic use is associated with worse outcomes in patients with gastrointestinal or liver cancer receiving ICIs and should be carefully justified. Prospective studies are needed to validate these results.

Topics & Keywords

Cancer Immunotherapy and Biomarkers Inflammatory Biomarkers in Disease Prognosis Hepatocellular Carcinoma Treatment and Prognosis

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: The American Journal of Gastroenterology

DOI: 10.14309/ajg.0000000000003956

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