IFITM1 is required for epithelial mesenchymal transition in airway remodeling of allergic asthma

20261 citationsJournal Articlegold Open Access

Authors

Manni Zhu · Jiangsu Province Hospital

Xiaoqin Weng · Second Affiliated Hospital of Nanjing Medical University

Chuanli Zhang · Jiangsu Province Hospital

Xiaofei Song · Jiangsu Province Hospital

Shan Liu · Jiangsu Province Hospital

Tingting Xu · Jiangsu Province Hospital

Zhengxia Wang ·

Abstract

IFIMT1, which is upregulated in airway epithelial cells via the IFN-β and STAT1 signaling pathways, contributes to EMT during allergic airway remodeling and may serve as a potential treatment target for allergic asthma.

Topics & Keywords

Asthma and respiratory diseases Immune Response and Inflammation IL-33, ST2, and ILC Pathways

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: World Allergy Organization Journal

Volume 19, Issue 3, pp. 101339-101339

DOI: 10.1016/j.waojou.2026.101339

Field-Weighted Citation Impact: 33.37