Intracranial pressure, neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, C-reactive protein, and D-dimer mortality predictors in isolated severe traumatic brain injury

An initial ICP exceeding 20 cmH2O (14.71 mmHg) may serve as a new predictive threshold for 14-day mortality in isolated STBI patients. In addition, low PLR (<90.63) may serve as an early mortality predictor. Further studies are needed to clarify the role of other biomarkers.