Video-assisted thoracoscopy with pleurodesis as treatment of amiodarone induced recurrent pleural effusion

53-year-old male with recurrent right pleural effusion secondary to chronic use of amiodarone. The patient required multiple thoracenteses, and despite amiodarone dose reduction effusion recurred. Video-assisted thoracoscopy with unilateral mechanical pleurodesis and decortication were done, with complete resolution and no recurrence of the effusion even with the amiodarone on board. Surgical approach for unilateral pleural effusion due to amiodarone that is resistant to the standard treatment, may be a strategy in patients where amiodarone cannot be discontinued.