The association of Apolipoprotein E ε4 with symptomatic intracerebral hemorrhage, MRI markers and cognition in Dutch-type hereditary cerebral amyloid angiopathy

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Authors

Maaike C. van der Plas · Leiden University Medical Center

Rosemarie van Dort · Leiden University Medical Center

Ingeborg Rasing · Leiden University Medical Center

Yongxi Long · Leiden University Medical Center

Erik W. van Zwet · Leiden University Medical Center

Matthias J.P. van Osch · Leiden University Medical Center

Hamid R. Sohrabi

Abstract

APOE ε4 does not affect key clinical parameters or D-CAA neuroradiological markers and therefore does not explain the large variation in disease course in D-CAA.

Topics & Keywords

Intracerebral and Subarachnoid Hemorrhage Research Alzheimer's disease research and treatments Cerebrovascular and genetic disorders

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Journal of Stroke and Cerebrovascular Diseases

Volume 35, Issue 4, pp. 108593-108593

DOI: 10.1016/j.jstrokecerebrovasdis.2026.108593

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