Assessing symptom severity in patients with markedly treatment-resistant depression: Insights from the RECOVER trial

20260 citationsJournal Articlehybrid Open Access

Authors

A. John Rush · Duke-NUS Medical School

Harold A. Sackeim · Medical University of South Carolina

Ying-Chieh Lee · LivaNova (United Kingdom)

Charles R. Conway · Washington University in St. Louis

Scott T. Aaronson · Sheppard Pratt Health System

Mark Bunker · LivaNova (United Kingdom)

João Quevedo

Abstract

The MADRS, QIDS-C, and QIDS-SR are suitable for use in markedly TRD. Whether sadness, energy, interest, guilt, and concentration are "core" symptoms that are especially sensitive to change deserves further study.

Topics & Keywords

Treatment of Major Depression Mental Health Research Topics Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes

Publication Details

Published in: Journal of Affective Disorders

Volume 403, pp. 121447-121447

DOI: 10.1016/j.jad.2026.121447

Field-Weighted Citation Impact: 0.00

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Assessing symptom severity in patients with markedly treatment-resistant depression: Insights from the RECOVER trial

Authors

Abstract

Topics & Keywords

Publication Details