Serological screening for cytomegalovirus in a leucodepleted blood supply: A systematic review

20260 citationsJournal Article

Authors

Philip Crispin · Australian National University

Danielle Edwards · Hunter New England Local Health District

Karen Beattie · National Blood Transfusion Service

Kristen Brown · National Blood Transfusion Service

Lisa Clarke · Australian Red Cross Lifeblood

Fiona King · National Blood Transfusion Service

Amanda Ormerod

Abstract

Selecting CMV-seronegative donors did not reduce the risk of transmission when transfusing leucodepleted blood products because of the high efficiency of filters in removing transmissible cellular virus. This finding suggests CMV donor negative selection does not substantially contribute to donor safety.

Topics & Keywords

Cytomegalovirus and herpesvirus research Erythrocyte Function and Pathophysiology Parvovirus B19 Infection Studies

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Vox Sanguinis

DOI: 10.1111/vox.70219

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