Melatonin-Loaded Sacchachitin Nanofiber Hydrogel as a Novel Non-Steroidal Platform for Atopic Dermatitis Therapy

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Authors

Chien-Ju Lin · Kaohsiung Medical University

Baole Wen · Yuanpei University

Yu-Kai Liang · Chia Nan University of Pharmacy and Science

Wen-Chen You · Taiwan Food and Drug Administration

Hsiu-O Ho · Taipei Medical University

Ming-Thau Sheu · GenMont Biotech (Taiwan)

H. R. Lin ·

Abstract

The melatonin-loaded SCNF hydrogel represents a promising non-steroidal and biocompatible topical platform for AD. In this system, SCNF primarily serves as a structural scaffold, whereas melatonin provides immunomodulatory and anti-inflammatory activity. These findings support further translational investigation.

Topics & Keywords

Dermatology and Skin Diseases Advancements in Transdermal Drug Delivery Skin Protection and Aging

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: International Journal of Nanomedicine

Volume Volume 21, pp. 1-18

DOI: 10.2147/ijn.s574853

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