Thermodynamic Properties of HFE-7300

Abstract Hydrofluoroethers (HFEs) are considered promising replacements for the high global warming potential (GWP) per- and polyfluoroalkyl substances (PFAS) in refrigeration, heat transfer, and electronic cooling applications. However, the scarcity and inconsistency of available thermophysical property data have hindered their reliable implementation and modeling. This study reports a comprehensive experimental investigation of HFE-7300 (1,1,1,2,2,3,4,5,5,5-decafluoro-3-methoxy-4-(trifluoromethyl)pentane), including measurements of critical properties, density, vapor pressure, isobaric heat capacity, and speed of sound over wide temperature and pressure ranges. The experiments were complemented by ab initio calculations of ideal-gas thermodynamic properties, resulting in a consistent dataset suitable for model development. Correlations for vapor pressure, density, and heat capacities were derived and mutually validated for internal thermodynamic consistency. These results provide a robust foundation for developing a multiparameter equation of state for HFE-7300, while the performance of cubic, PC-SAFT, and LKP equations of state was also evaluated as an interim approach.