Plasma p‐tau217 predicts PET‐based pathological staging for precision Alzheimer disease assessment

20260 citationsJournal Articlegreen Open Access

Authors

Han‐Kyeol Kim · Wonju Severance Christian Hospital

Jae Hoon Lee · Gangnam Severance Hospital

Joong‐Hyun Chun · Severance Hospital

You Jin Kim · Gangnam Severance Hospital

Mina Park · Gangnam Severance Hospital

Tim West · C2N Diagnostics (United States)

Kristopher M. Kirmess

Abstract

Plasma p-tau217-based biomarkers accurately reflect PET-based staging across frameworks. The convergent therapeutic window thresholds demonstrate robust biological transitions, enabling accessible identification of optimal candidates for disease-modifying therapies.

Topics & Keywords

Dementia and Cognitive Impairment Research Alzheimer's disease research and treatments Medical Imaging Techniques and Applications

UN Sustainable Development Goals

Reduced inequalities

Publication Details

Published in: Alzheimer s & Dementia

Volume 22, Issue 2, pp. e71199-e71199

DOI: 10.1002/alz.71199

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