Diagnostic value of cellular inflammatory markers in CNS tumor patients undergoing glucocorticoid therapy

20260 citationsJournal Articlegold Open Access

Authors

Sofia Sklyar · Russian Scientific Research Neurosurgical Institute

Daria Sitovskaya · Russian Scientific Research Neurosurgical Institute

Nataliya Dryagina · Russian Scientific Research Neurosurgical Institute

Alexei Ulitin · Federal Almazov North-West Medical Research Centre

Victor E. Olyushin · Russian Scientific Research Neurosurgical Institute

Stephanie E. Combs · Technical University of Munich

Abstract

For patients with glioblastoma, the LMR serves as a diagnostically significant inflammatory biomarker independent of glucocorticoid administration. In patients with metastatic brain lesions, the most significant diagnostic value was demonstrated by monocyte counts, PIV and LMR.

Topics & Keywords

Inflammatory Biomarkers in Disease Prognosis Glioma Diagnosis and Treatment Immune cells in cancer

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Frontiers in Oncology

Volume 16, pp. 1764339-1764339

DOI: 10.3389/fonc.2026.1764339

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