Protocol of ASPro-PD: a phase 3 trial of ambroxol to slow progression in genetically stratified Parkinson’s disease

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Authors

Marco Toffoli · Queen Mary University of London

Elisa Menozzi · Queen Mary University of London

Mairead Cullen · MRC Clinical Trials Unit at UCL

Kashfia Chowdhury · MRC Clinical Trials Unit at UCL

Saiam Ahmed · MRC Clinical Trials Unit at UCL

Nick Freemantle · MRC Clinical Trials Unit at UCL

Joy Duffen

Abstract

This trial is the largest to date to study the effect of ambroxol in PD, utilise a genetically stratified PD population and will provide robust estimates of the efficacy of ambroxol in slowing PD clinical progression.

Topics & Keywords

Parkinson's Disease Mechanisms and Treatments Lysosomal Storage Disorders Research Cystic Fibrosis Research Advances

Publication Details

Published in: Journal of Neurology

Volume 273, Issue 2, pp. 151-151

DOI: 10.1007/s00415-026-13683-7

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Protocol of ASPro-PD: a phase 3 trial of ambroxol to slow progression in genetically stratified Parkinson’s disease

Authors

Abstract

Topics & Keywords

Publication Details