Oncogenic LPCAT1 Accelerates Intrahepatic Cholangiocarcinoma Development Through PI3K/Akt Signaling‐Dependent Cell Cycle Regulation

20260 citationsJournal Article

Authors

Enlai Jiang · Army Medical University

Yuwei Chen · Sichuan University

Menglin Chen · Sichuan University

Yongjie Zhou · Sichuan University

D. Zheng · Army Medical University

Qing Xu · Army Medical University

Abstract

LPCAT1 upregulates cell cycle proteins through activation of the PI3K/AKT signaling pathway, thereby promoting cellular proliferation and accelerating ICC progression.

Topics & Keywords

Protein Kinase Regulation and GTPase Signaling Lipid metabolism and biosynthesis Cholesterol and Lipid Metabolism

Publication Details

Published in: Journal of Gastroenterology and Hepatology

DOI: 10.1111/jgh.70291

Field-Weighted Citation Impact: 0.00

Command Palette

Oncogenic LPCAT1 Accelerates Intrahepatic Cholangiocarcinoma Development Through PI3K/Akt Signaling‐Dependent Cell Cycle Regulation

Authors

Abstract

Topics & Keywords

Publication Details