Overview of Coenzyme Q10 and its role in enhancing sport performance

Background Among the many antioxidative substances tested as supplements in various sports, coenzyme Q10 appears to be one of the most promising in terms of improving physical endurance. As a part of mitochondrial respiratory chain, as well as a membrane antioxidant, its supplementation has a sound theoretical basis, as it may enhance energy production in muscles and protect them from oxidative stress, potentially leading to improved sports performance. Aim The aim of this study is to summarize the current knowledge regarding the impact of coenzyme Q10 supplementation on sport performance. Materials and methods A systematic literature review was conducted using PubMed and Google Scholar. The following search terms were used: “coenzyme Q10”, “exercise”, “sports”, and “mind sports”. Only English-language publications were analysed for possible inclusion in this review, with double-blind and single-blind, placebo-controlled studies being prioritised. Conclusions The studies included in this review showed contradictory results. Some demonstrated significant improvements in subjects’ physical fitness, while others showed no differences between the groups. Larger studies and meta-analyses on this topic should be conducted to more precisely evaluate the potential benefits of coenzyme Q10 supplementation.