FAM216A Promotes Hepatocellular Carcinoma Proliferation and Invasion through the PLK1/ERK Signaling Pathway

20260 citationsJournal Article

Authors

Peng Ma · Wuhan University

Ying Hao · Wuhan University

Yuefeng Zhang · Wuhan University

Weiguo Tang · Fudan University

Wei Wang · Wuhan University

Zuo Muo · Wuhan University

Abstract

FAM216A is overexpressed in HCC tissues and is associated with poor clinical outcomes. Mechanistically, FAM216A promotes aggressive tumor behavior by activating the PLK1/ERK signaling pathway.

Topics & Keywords

Angiogenesis and VEGF in Cancer Cell Adhesion Molecules Research Wnt/β-catenin signaling in development and cancer

UN Sustainable Development Goals

No poverty

Publication Details

Published in: Genetic Testing and Molecular Biomarkers

Volume 30, Issue 3, pp. 55-66

DOI: 10.1177/19450265261417993

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