Template-Directed RIG-I Agonist Assembly for Image-guided Targeted Cancer Immunotherapy

20260 citationsJournal Articlehybrid Open Access

Authors

Subrata K. Ghosh · Io Therapeutics (United States)

Douglas Lazarus · BioClinica (United States)

Neil Robertson · Io Therapeutics (United States)

Qiyong Liu · Io Therapeutics (United States)

Elizabeth Kenyon · Michigan State University

Christian L. Mallett · Michigan State University

Ming Chen

Abstract

Our template-driven approach brings RIG-I closer to becoming a clinically relevant target in oncology by specifically activating immune responses within tumor cells through systemic RIG-I agonist delivery.

Topics & Keywords

interferon and immune responses Advanced biosensing and bioanalysis techniques Nanoplatforms for cancer theranostics

UN Sustainable Development Goals

Good health and well-being

Publication Details

Published in: Molecular Imaging and Biology

DOI: 10.1007/s11307-026-02087-8

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