Paired Duodenal and Salivary Microbiome Analysis in Pancreatic Cancer Without Duct Obstruction

20260 citationsJournal Articlehybrid Open Access

Authors

Livia Archibugi · Pancreas Centre (Canada)

Loris Bertoldi · Biomolecular Research Genomics (Italy)

Giuseppe Benvenuto · Biomolecular Research Genomics (Italy)

Eleonora Sattin · Biomolecular Research Genomics (Italy)

Ruggero Ponz De Leon Pisani · Pancreas Centre (Canada)

Claudia Fortunato · Pancreas Centre (Canada)

Alberto Mariani

Abstract

PDAC is associated with reduced duodenal phylogenetic diversity and subtle disease-related shifts in duodenal microbiota, independent of major confounders and in the absence of duct obstruction. Both α-diversity and selected genera may hold prognostic relevance, supporting further validation in larger, stage-stratified cohorts.

Topics & Keywords

Gut microbiota and health Oral microbiology and periodontitis research Salivary Gland Disorders and Functions

Publication Details

Published in: United European Gastroenterology Journal

Volume 14, Issue 2, pp. e70179-e70179

DOI: 10.1002/ueg2.70179

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Paired Duodenal and Salivary Microbiome Analysis in Pancreatic Cancer Without Duct Obstruction

Authors

Abstract

Topics & Keywords

Publication Details